Core technology

Intelligent Substrates has developed patented and proprietary technologies related to protein patterning and its applications.

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ISI's protein micro patterning technology is fast and flexible.

It can produce protein micropatterns on virtually any material commonly used in cell culture in any desired format.

Pattern feature sizes can range from microns to millimeters and larger.

The micropatterns have a uniform protein density and clean, sharp edges for better cell response.

And while our focus is on components of the extracellular matrix, we are not limited to those proteins.

ISI has confirmed that a number of cell types respond to our micropatterned substrates. We are actively determining the responses of other cell lines. If there is a cell line you are interested in that is not listed here, please contact us.

Proteins

Fibronectin
Laminins
Collagens
Fibrinogen
ECM mimics
Others

Formats

Coverslips
Petri dishes
Glass-bottom dishes
Slides
Multiwell plates (2013)
Custom formats

Materials

Glass
Polystyrene
PDMS
Cyclic polyolefin polymers
Silicon
Quartz

Verified cell lines

Swiss-3T3
HUVEC
CHO
MCF-7
B16-F10
SMC
HDF
More coming soon.
MDA-MB-231
PC-12
WI-38
B16-F1